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Cheesy Pepperoni Beef Pizza Enchiladas

A hearty fusion dish marrying the flavors of classic pizza and zesty enchiladas. Soft flour tortillas are packed with seasoned ground beef, robust pizza sauce, savory pepperoni, and gooey melted cheese, then baked to perfection. This family-friendly dinner is fast, flavorful, and sure to be a crowd-pleaser.
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Course: Dinner, Main Course
Cuisine: American
Keyword: Cheesy Pepperoni Beef Pizza Enchiladas
Prep Time: 15 minutes
Cook Time: 25 minutes
Total Time: 40 minutes
Servings: 6

Ingredients

  • 6 soft flour tortillas 8-inch size
  • 2 tablespoons of olive oil or melted butter for coating the baking dish
  • 1 pound lean ground beef
  • 1/2 cup of chopped mini pepperoni or roughly diced standard pepperoni slices
  • 1 1/2 cups shredded mozzarella cheese separated
  • 1/4 cup finely grated Parmesan
  • 1 small yellow onion finely diced
  • 3/4 cup pizza sauce for the filling plus 3/4 cup for topping
  • 1 teaspoon dried Italian herb mix
  • 1/2 teaspoon ground garlic powder
  • 1/4 teaspoon crushed red chili flakes optional, for heat
  • Fresh basil leaves or chopped parsley for finishing garnish

Instructions

  • Preheat your oven to 375°F (190°C). Lightly grease a 9x13-inch baking dish with olive oil or butter, ensuring even coverage across the bottom and sides.
  • Place a large skillet over medium heat. Add the ground beef and finely chopped onion. Cook, stirring occasionally, until the beef is thoroughly browned and the onions have softened.
  • Season the cooked beef with Italian seasoning, garlic powder, and optional red pepper flakes. Stir well, then drain any excess fat from the skillet.
  • Pour in 3/4 cup of the pizza sauce and mix to coat the beef evenly. Let it simmer briefly, then remove from heat.
  • Lay out each tortilla on a clean surface. Spoon a generous amount of the beef mixture onto the center of each one. Add a sprinkle of shredded mozzarella and a portion of chopped pepperoni.
  • Tightly roll up the tortillas, enclosing the filling, and arrange them seam-side down in the prepared baking dish.
  • Spoon the remaining 3/4 cup of pizza sauce over the assembled enchiladas. Sprinkle the top evenly with the rest of the mozzarella and the grated Parmesan. Add extra pepperoni slices on top if desired.
  • Cover the dish loosely with foil and place in the oven. Bake for 15 minutes, then remove the foil and continue baking for an additional 10 minutes, or until the cheese is melted, bubbly, and golden.
  • Once baked, remove from the oven and let cool slightly. Garnish with freshly chopped parsley or torn basil leaves just before serving.

Notes

Pair with a crisp garden salad or warm garlic bread for a complete meal. Adjust spice levels by omitting or increasing the red pepper flakes to your preference.